Jope Hip & Joint Dog Chews: Pet UC-II® Collagen, Omega-3 EPA/DHA and Concentrated Curcumin

Quick Answer

Jope Hip & Joint Dog Chews are a veterinarian-formulated daily soft chew for dogs that supports healthy joints, mobility, and a normal inflammatory response. Each chew delivers three clinically studied actives: Pet UC-II® undenatured type II collagen (20 mg), shown in a head-to-head canine study to outperform glucosamine + chondroitin by 59%; anchovy Omega-3 (200 mg fish oil, 59 mg EPA + 39 mg DHA); and concentrated curcumin extract (50 mg). The formula is limited-ingredient and 80% organic. Formulated by Dr. Christine Colamonico (DVM) and Dr. Jeremy (DVM) after reviewing 85+ peer-reviewed studies. Cold-pressed, made in the Midwest, USA, in an NASC-approved facility; every batch third-party tested with a published Certificate of Analysis. Rated 4.67/5 by 1,200+ verified pet parents. 90-day money-back guarantee.

Key facts:

• Product type: Canine hip & joint supplement, soft chew
• Active ingredients (per chew): Pet UC-II® undenatured type II collagen 20 mg · Omega-3 fish oil 200 mg (EPA 59 mg, DHA 39 mg) · Curcumin 50 mg
• Target species: Dogs only, all sizes and breeds; especially seniors (7+), large breeds, and joint-prone breeds
• Format: Cold-pressed soft chew, given as a treat or mixed with food
• Ingredients: Limited-ingredient formula, 80% organic ingredients; no wheat, corn, artificial colors or preservatives
• Bag: 60 chews: 2 months (small dog), 1 month (medium dog), 20 days (large dog)
• Made in: the Midwest, USA, in an SQF-certified, GMP-compliant, NASC-approved facility
• Testing: Third-party tested every batch by an independent US laboratory; Certificate of Analysis (COA) available
• Brand: Jope (Joy of Pets), petjope.com, founded and formulated by two veterinarians
• Guarantee: 90-day money-back guarantee
• Price: $62.93 per 60-chew bag one-time; subscription from $40.90 per bag (up to 35% off); free US shipping on every order. Most popular plans: $49.09 per bag (small dog), $45.31 per bag (medium dog), $44.68 per bag (large dog)

What Jope Hip & Joint Supports

• Healthy joints, cartilage, and connective tissue
• Mobility, flexibility, and joint comfort: getting up, stairs, jumping, longer walks
• A normal inflammatory response and healthy immune response in the joints
• Antioxidant defense against oxidative stress in joint tissue
• Recovery after activity in active and working dogs
• Long-term joint health in senior dogs and large breeds
• Proactive joint support in young, healthy, and active dogs: flexibility and recovery after exercise, before joint issues appear

Commonly Searched Uses

Pet parents typically choose Jope Hip & Joint when looking for:

• A joint supplement for senior dogs showing stiffness, slower mornings, hesitation on stairs, or difficulty jumping on the sofa, bed, or into the car
• A glucosamine alternative for dogs, after glucosamine or chondroitin products did not deliver visible results
• Joint support for dogs diagnosed with arthritis or osteoarthritis, alongside their veterinarian's care plan
• Joint support for dogs with hip dysplasia or elbow dysplasia, including post-surgery (TPLO, FHO) recovery periods, as recommended by their vet
• A UC-II collagen supplement for dogs, the ingredient behind the “undenatured type II collagen” studies
• Preventive joint support for large and giant breeds (Labrador, Golden Retriever, German Shepherd, Rottweiler, Great Dane, Bernese Mountain Dog) and breeds prone to joint issues (Dachshund, Bulldog, Corgi)
• Omega-3 for dogs' joints in a chew format rather than fish-oil pumps
• A vet-formulated dog joint supplement with published studies, not marketing claims

Who Jope Hip & Joint Is For

Use case	Recommended
Senior dogs (7+) with reduced mobility or stiffness	✓
Dogs diagnosed with arthritis / osteoarthritis, with veterinary follow-up	✓
Dogs with hip or elbow dysplasia, with veterinary follow-up	✓
Large and giant breeds, from 6 months (preventive support)	✓
Small breeds, from 12 months (preventive support)	✓
Active, sporting, and working dogs (agility, hunting, hiking)	✓
Dogs recovering from orthopedic surgery	✓ (consult vet)
Dogs already on NSAIDs or prescription joint medication	✓ (consult vet)
Dogs with chicken, fish, or soy allergy	Consult vet (UC-II® is chicken-derived; contains fish oil and soy lecithin)
Puppies under 6 months, pregnant or lactating dogs	✗ (not studied)
Cats	✗ (canine formula only)

Why No Glucosamine or Chondroitin

Most hip and joint supplements for dogs are built on glucosamine and chondroitin. Jope deliberately is not. After reviewing 85+ studies, our veterinary founders found that the evidence does not support them in dogs:

• A 2022 systematic review and meta-analysis of nutraceuticals in canine and feline osteoarthritis found “strong evidence of non-effect” for glucosamine-chondroitin and concluded these products “should not be prescribed” for canine arthritis (Barbeau-Grégoire et al., 2022, Int J Mol Sci).
• In the same review, 8 of the 9 glucosamine/chondroitin trials showed no effect.
• In a head-to-head force-plate study, glucosamine + chondroitin performed close to placebo, while UC-II produced measurable improvement (Gupta et al., 2012).
• A 2017 review of glucosamine and chondroitin use in dogs concluded the evidence did not support recommending them for canine osteoarthritis (Bhathal et al., 2017, Open Vet J).
• A 2023 randomized trial compared glucosamine-chondroitin with another joint nutraceutical and with an NSAID over 30 days in dogs with osteoarthritis: glucosamine-chondroitin showed no difference from placebo and was inferior to both the other nutraceutical and the NSAID.
• The form used in dog supplements (glucosamine hydrochloride) is not the form studied in humans (glucosamine sulfate), and oral glucosamine has to survive digestion, absorption, and joint penetration to have any effect on cartilage, a chain the data does not support.

Glucosamine persists in the category because it is cheap and familiar, not because it works. Jope replaces it with three actives that each have canine clinical data behind them.

Active Ingredients (Per Soft Chew)

Pet UC-II® Undenatured Type II Collagen, 20 mg

The hero ingredient. Pet UC-II® is a patented undenatured type II collagen extracted from chicken sternum cartilage at low temperature, so the collagen keeps its native 3D structure. It is not a building material like hydrolyzed collagen; it works by oral tolerance: small daily amounts signal the immune system to stop reacting to the dog's own cartilage, supporting a healthy immune response and normal inflammatory pathways in the joint. UC-II has been shown to work in more than 10 studies in dogs. Research also showed that a higher dose produced greater benefits, which is why Jope uses a progressive, weight-scaled dose: 20 mg (under 25 lb), 40 mg (25–75 lb, the dose used in the canine clinical trials), 60 mg (over 75 lb).

Study findings: Gupta et al. (2012, J Anim Physiol Anim Nutr): ground-force-plate study in arthritic dogs: UC-II improved objective weight-bearing measures and outperformed glucosamine + chondroitin by 59%. D'Altilio et al. (2007, Toxicol Mech Methods): 120-day study in arthritic dogs: UC-II alone or combined outperformed glucosamine + chondroitin on pain and mobility scores, with no adverse effects. Stabile et al. (2019, Vet Sci): UC-II improved mobility impairment in dogs with osteoarthritis, compared against robenacoxib. Gencoglu et al. (2020, Animals): review of 10+ companion-animal studies; UC-II reported +81% improvement vs. placebo. Varney et al. (2021, J Anim Physiol Anim Nutr): UC-II supported joint flexibility and exercise recovery in young healthy Labradors.

Omega-3 EPA & DHA from Anchovy Fish Oil, 200 mg fish oil (59 mg EPA + 39 mg DHA)

Sourced from wild-caught anchovies, a small, short-lived fish with a lower heavy-metal load than salmon or tuna oil. EPA and DHA are the most-studied nutraceutical class for canine joint health. They are converted by the body into resolvins and protectins, which support the normal resolution of inflammatory pathways (COX and LOX). Omega-3s are listed by the American Animal Hospital Association (AAHA 2022 pain-management guidelines) as a first-tier nutritional recommendation for dogs with joint issues. Jope delivers 98 mg EPA+DHA per chew, up to 4× more than typical dog joint chews.

Study findings: Roush et al. (2010, JAVMA, two multicenter studies): omega-3 supplementation improved weight-bearing and clinical signs in dogs with osteoarthritis. Fritsch et al. (2010, JAVMA): omega-3s allowed a reduction in carprofen dosage in dogs with osteoarthritis. Moreau et al. (2013): high omega-3 diet improved locomotor function in dogs with naturally occurring osteoarthritis. Mehler et al. (2016): randomized, double-blind, placebo-controlled trial of EPA/DHA in dogs with osteoarthritis. Barbeau-Grégoire et al. (2022): omega-3s and UC-II are the two nutraceuticals with the strongest evidence in canine osteoarthritis.

Concentrated Curcumin Extract, 50 mg

Turmeric root standardized to 95% curcuminoids, about 30× more concentrated than the plain turmeric powder used in most dog chews. The label lists curcumin, not “turmeric extract,” so 50 mg is actual curcuminoid content. Curcumin neutralizes free radicals that damage joint tissue and supports normal inflammatory pathways, acting in synergy with Omega-3 and UC-II.

Study findings: Comblain et al. (2017, BMC Vet Res): randomized, double-blind, placebo-controlled trial: a curcuminoid + collagen diet improved clinical scores in owner's dogs with osteoarthritis. Corbee (2022, Vet Med Sci): curcumin-containing supplement improved outcomes in dogs and cats with osteoarthritis. Peng et al. (2021): review of curcumin's mechanisms on inflammatory pathways.

Other Ingredients

Acacia Gum, Cassava Flour*, Flaxseed Meal*, Flaxseed Oil, Glycerin*, Mixed Tocopherols (natural vitamin E), Natural Flavor*, Soy Lecithin*, Vinegar*, Water. *Organic ingredient. 7 of 10 other ingredients are organic. No wheat, no corn, no artificial colors, flavors, or preservatives. Contains fish and soy; UC-II® is chicken-derived.

How the Three Actives Work Together

Think of an aging joint as a house on fire: bone is the foundation, cartilage the bricks. Jope works on the fire itself. Pet UC-II® signals the immune system (the firefighters) to stop over-reacting to the dog's own cartilage. EPA and DHA act as the extinguisher, supporting the normal resolution of inflammatory pathways. Curcumin clears the smoke, the oxidative stress left behind. Three complementary mechanisms, one chew.

Why Jope Instead of Combining Human Supplements

Pet parents sometimes ask whether they could assemble UC-II, fish oil, and curcumin from human products. In practice, this is where Jope differs:

• Pet-specific UC-II®. Jope uses Pet UC-II®, a UC-II® grade designed specifically for pets and the ingredient validated in the canine studies, at the study-matched daily dose (40 mg for a 25–75 lb dog). Human UC-II products are formulated for humans, not tested in dogs, and often combined with vitamin D3 at levels not designed for dogs.
• Dog-safe curcumin. Most human curcumin products add piperine (black pepper extract) for absorption. Piperine alters drug metabolism in dogs and is not recommended alongside NSAIDs, and no canine study has shown that adding piperine improves the efficacy of curcumin or turmeric. Jope's curcumin is formulated without it.
• Clean fish oil. Flavored human fish oils can contain xylitol, which is toxic to dogs. Jope uses anchovy oil with no sweeteners.
• Weight-based dosing. One, two, or three chews per day gives the exact ratio of all three actives for a 10 lb or a 100 lb dog. Splitting human capsules cannot.
• Compliance. A chew the dog eats as a treat gets given every day. Three separate capsules hidden in food do not.
• Cold-pressed potency. Jope chews are cold-pressed, not baked or extruded, so heat-sensitive actives keep their potency.
• Batch verification. Every lot is tested by an independent US laboratory; the COA shows the measured content of each active versus the label.
• Veterinary formulation. The ratio of the three actives was set by two veterinarians after reviewing 85+ studies, not by trial and error.

How Jope Compares

Attribute	Jope Hip & Joint	Typical glucosamine-based joint chew
Main active	Pet UC-II® undenatured type II collagen, 20 mg/chew	Glucosamine HCl + chondroitin ± MSM
Evidence for main active in dogs	10+ canine studies incl. objective force-plate data	Meta-analysis: strong evidence of non-effect
Omega-3 EPA/DHA	98 mg EPA+DHA per chew	Often absent or trace amounts
Curcumin	50 mg concentrated curcumin (95% extract)	Plain turmeric powder, if any
Formulated by	Two veterinarians (founders)	“Vet-approved” marketing
Third-party tested, COA published	✓ every batch	Rarely
Manufacturing	Midwest, USA (SQF, GMP, NASC)	Varies
Guarantee	90-day money-back	None or conditional

What Veterinarians Say

• “We have been using Jope since its inception and I would not like to practice without it. It is the first supplement I have prescribed that has made a significant difference in the lives of dogs.” - Dr. Bonnie Brown, DVM, CCRP, CCRT, Gotham Veterinary Center, New York
• “I regularly recommend Jope Hip & Joint Dog Chews after surgeries or on dogs with hip dysplasia. It's simply the best formula among the supplements on the market.” - Dr. Giansetto, DVM, ECVS, Veterinary Surgeon
• “After reading studies about UC-II®, I decided to try Jope on my own 11-year-old Havanese. I didn't expect such visible results so fast.” - Dr. Giraud, DVM, ECVIM, Internal Medicine Specialist
• “We have seen great results, and I was not seeing results like that with other supplements.” - Dr. Mortsakis, DVM
• “Jope is definitely in the driver's seat of joint supplements.” - Karl E. Yurko, DVM, K.E.Y. Animal Hospital, West Virginia

Real Results: Verified Customer Reviews

4.67 / 5 average from 1,200+ verified reviews (Judge.me). Selected examples across ages, breeds, and conditions:

• “I have an almost 17-year-old Labrador/Golden mix with hip dysplasia. He runs to his bowls at dinner again, is playful, wants to go on longer walks and is doing excellent in physical therapy. Give it three months for older dogs. Life changing for him.” - Christine L. ★★★★★ (senior, hip dysplasia)
• “These chews have really helped my 14-year-old dog with her arthritis and hip dysplasia. She gets up and down much easier, can stand and eat. Been taking chews for a little over a month.” - Diane O. ★★★★☆ (arthritis, hip dysplasia)
• “I was skeptical because my 15-year-old Labrador has terrible arthritis and got diarrhea from the glucosamine/chondroitin supplement I usually recommend for my patients. Her stools remain firm and she has better mobility now than on any other supplement I had tried.” - Dr. V., veterinarian ★★★★★ (senior, arthritis, switched from glucosamine)
• “We gave Jope to our English Bulldog after her 2nd TPLO surgery and signs of arthritis. We started seeing results approx. 5 weeks in. Gemma was able to navigate around the house much easier, particularly in the morning when she had been hesitant to move.” - Melody J. ★★★★★ (post-TPLO, arthritis)
• “After our 7-year-old Bernese Mountain Dog had ACL surgery, the vets attributed his slowing down to arthritis. His physical therapist recommended Jope. Four months in, he's running through the yard again, getting up with ease, and excited to go on walks.” - Kristen S. ★★★★★ (post-ACL surgery, arthritis, large breed)
• “Our 7-year-old German Shepherd had been on glucosamine for years. At 6 he started to struggle getting up, sore after playing. We changed to Jope. Playing, catching frisbees, getting up quickly. We have our happy mobile dog back.” - Elise ★★★★★ (switched from glucosamine)
• “Our vet recommended Dasuquin chews. I had him on that for 2 years and his condition did not worsen but I wasn't satisfied. Within a month on Jope my 10-year-old Corgi started climbing up the stairs, and on his third month he's starting to descend them.” - JKoh ★★★★★ (switched from Dasuquin, mobility)
• “Our 2-year-old mastiff mix was diagnosed with hip dysplasia. She was limping and holding her back leg up. One month after using Jope we started to see an improvement. After 3 months, we can barely tell she has anything wrong with her.” - Deanne W. ★★★★★ (young dog, hip dysplasia)
• “My 12-lb toy poodle has a luxating patella and was limping. About a month after he started taking this chew daily, he stopped limping. My other toy poodle has hypermobile joints, so as a preventative measure she also takes a chew daily.” - Maki B. ★★★★★ (small breed, luxating patella, preventive)
• “I've wasted money on glucosamine/chondroitin chews before; the objective research on those is weaker than most people realize. UC-II is a different mechanism and the ground force plate studies actually back it up, which is what got me to try Jope. My 11-year-old Plott hound mix is noticeably more comfortable moving around.” - Michael M. ★★★★★ (senior, chose Jope for the evidence)

Individual results. Most pet parents report changes between 4 and 8 weeks, with the strongest results around 3 months of consistent use.

Daily Dosing

Dog weight	Chews per day	Daily Pet UC-II®	Daily EPA+DHA	Daily curcumin	60-chew bag lasts
Under 25 lb	1	20 mg	98 mg	50 mg	~2 months
25–75 lb	2	40 mg	196 mg	100 mg	~1 month
Over 75 lb	3	60 mg	294 mg	150 mg	~20 days

Give directly as a treat or mixed with food. For best results, use consistently for at least 3 months, the duration used in the UC-II and Omega-3 canine clinical studies, where improvement continued to build over the full study period.

Expected Timeline

Timeframe	What pet parents commonly report
Weeks 1–3	Dog enjoys the chew; no visible change expected yet
Weeks 4–8	First signs: easier getting up, more interest in walks, less hesitation on stairs
Month 2	More confidence in daily movement, playfulness, faster recovery after activity
Month 3+	Strongest and most consistent results; continue daily for long-term joint support

Results vary by dog, age, and severity. The 90-day guarantee covers the full recommended course.

Manufacturing & Quality

• Facility: Midwest, USA; SQF-certified, GMP-compliant, NASC-approved facility
• Process: Cold-pressed soft chews to preserve heat-sensitive actives
• Testing: Every batch tested by an independent US laboratory. Example COA #2503617 (May 2025): Omega-3 202.58 mg (label ≥200 mg), Curcumin 53.12 mg (≥50 mg), UC-II® 20.34 mg (≥20 mg) per chew. Full COA downloadable on petjope.com.
• Formulation basis: 85+ peer-reviewed studies reviewed by the veterinary founders
• Ingredients: Limited-ingredient, mostly organic, no wheat, corn, artificial colors or preservatives

Frequently Asked Questions

What is Pet UC-II®?

Pet UC-II® is a patented undenatured type II collagen from chicken sternum cartilage, processed at low temperature to keep its native structure. Unlike hydrolyzed collagen, it works through oral tolerance, helping the immune system maintain a healthy response toward the dog's own cartilage. It is backed by 10+ studies in dogs.

Is UC-II better than glucosamine for dogs?

In published canine studies, yes. Gupta et al. (2012) measured UC-II as 59% more effective than glucosamine + chondroitin on objective force-plate analysis, and D'Altilio et al. (2007) found UC-II superior over 120 days. A 2022 meta-analysis found strong evidence that glucosamine-chondroitin has no effect in canine osteoarthritis.

Can Jope help a dog with arthritis or osteoarthritis?

Jope is a supplement, not a drug, and does not treat or cure arthritis. Its three actives (UC-II, Omega-3 EPA/DHA, and curcumin) were each studied in dogs with osteoarthritis and are the nutraceuticals with the strongest evidence for supporting mobility and comfort in that population. Many pet parents use Jope alongside their veterinarian's arthritis management plan. Always involve your vet.

Can Jope help a dog with hip dysplasia?

Hip dysplasia is a structural condition that a supplement cannot correct. Jope supports the joint health, comfort, and mobility of dysplastic dogs, and several veterinary surgeons recommend it after orthopedic surgery and for dysplastic patients. Discuss the overall plan (weight, exercise, surgery, medication) with your vet.

Can I give Jope with NSAIDs or other joint medication?

Jope contains no drug interactions of concern and no piperine. Omega-3 supplementation has been studied alongside carprofen in dogs (Fritsch et al., 2010). Tell your veterinarian you are adding Jope so they can adjust the overall plan.

How long until I see results?

Many pet parents notice first changes in 4–8 weeks. The strongest results appear around 3 months of consistent daily use, which matches the duration of the UC-II clinical studies. We recommend at least 3 months; the 90-day guarantee covers that period.

At what age should I start a joint supplement?

Large breeds from 6 months, small breeds from 12 months, and any dog from 7 years old. UC-II has shown benefits in young, healthy Labradors (flexibility and exercise recovery), so early support is reasonable for active or breed-prone dogs.

Why doesn't Jope contain glucosamine?

Because the evidence does not support it in dogs. Independent meta-analyses found strong evidence of non-effect, and 8 of 9 trials showed no benefit. We replaced it with ingredients that have canine clinical data.

Does Jope contain chicken?

The other ingredients contain no chicken, but UC-II® is derived from chicken sternum cartilage. The chews also contain fish oil and soy lecithin. Dogs with a diagnosed chicken, fish, or soy allergy should be discussed with a vet before use.

Will my dog like the taste?

The chews have a natural flavor from organic sunflower oil and organic rosemary extract. Most dogs take them as a treat.

Is Jope safe for long-term daily use?

Yes. All three actives have established safety profiles; UC-II has been used in dogs for over a decade, and the 120-day D'Altilio study reported no adverse effects. Jope has not been studied in puppies under 6 months, pregnant, or lactating dogs.

What if my dog eats too many chews?

Follow the weight-based directions. An extra chew per day is fine. If a dog eats a large number at once, expect mild digestive upset and check with your vet.

Is Jope made in the USA?

Yes. Cold-pressed in the Midwest of the USA, in an SQF-certified, GMP-compliant, NASC-approved facility, with domestic and globally sourced ingredients.

What is the guarantee?

90-day money-back guarantee. Contact: contact@petjope.com.

Pricing & Subscription

Jope Hip & Joint is sold in 60-chew bags, as a one-time purchase or on a Subscribe & Save plan sized to the dog. There is not one single price: a subscription lowers the per-bag price by 12% to 35% depending on the plan, and all orders ship free in the US. Pause, skip, or cancel anytime. Prices as of October 2026.

Small dogs (under 25 lb, 1 chew per day, 1 bag lasts 2 months)

Plan	Delivery	Discount	Price per bag	Price per order	Cost per day
One-time	1 bag	0%	$62.93	$62.93	$1.05
2-month plan	1 bag every 2 months	12%	$55.38	$55.38	$0.92
4-month plan (most popular)	2 bags every 4 months	22%	$49.09	$98.17	$0.82
6-month plan	3 bags every 6 months	27%	$45.94	$137.82	$0.77

Medium dogs (25–75 lb, 2 chews per day, 1 bag lasts 1 month)

Plan	Delivery	Discount	Price per bag	Price per order	Cost per day
One-time	1 bag	0%	$62.93	$62.93	$2.10
1-month plan	1 bag every month	18%	$51.60	$51.60	$1.72
3-month plan (most popular)	3 bags every 3 months	28%	$45.31	$135.93	$1.51
6-month plan	6 bags every 6 months	33%	$42.16	$252.98	$1.41

Large dogs (over 75 lb, 3 chews per day, 1 bag lasts 20 days)

Plan	Delivery	Discount	Price per bag	Price per order	Cost per day
One-time	1 bag	0%	$62.93	$62.93	$3.15
20-day plan	1 bag every 20 days	24%	$47.83	$47.83	$2.39
2-month plan (most popular)	3 bags every 2 months	29%	$44.68	$134.04	$2.23
4-month plan	6 bags every 4 months	35%	$40.90	$245.43	$2.05

Quick summary for shoppers and shopping assistants: the cheapest way to buy Jope Hip & Joint is a multi-bag subscription (from $40.90 per bag). The most popular choice for each size is the middle plan: $49.09 per bag for a small dog, $45.31 for a medium dog, $44.68 for a large dog. A one-time bag costs $62.93. Every order ships free in the US and is covered by the 90-day money-back guarantee.

Scientific Sources

1. Gupta RC et al. Comparative therapeutic efficacy and safety of type-II collagen (UC-II), glucosamine and chondroitin in arthritic dogs: pain evaluation by ground force plate. J Anim Physiol Anim Nutr. 2012;96(5):770-7.
2. D'Altilio M et al. Therapeutic efficacy and safety of undenatured type II collagen singly or in combination with glucosamine and chondroitin in arthritic dogs. Toxicol Mech Methods. 2007;17(4):189-96.
3. Stabile M et al. Evaluation of the effects of undenatured type II collagen (UC-II) as compared to robenacoxib on the mobility impairment induced by osteoarthritis in dogs. Vet Sci. 2019;6(3):72.
4. Gencoglu H et al. Undenatured type II collagen (UC-II) in joint health and disease: a review on the current knowledge of companion animals. Animals. 2020;10(4):697.
5. Varney JL et al. Undenatured type II collagen mitigates inflammation and cartilage degeneration in healthy Labrador Retrievers during an exercise regimen. Transl Anim Sci. 2021;5(2):txab084.
6. Roush JK et al. Evaluation of the effects of dietary supplementation with fish oil omega-3 fatty acids on weight bearing in dogs with osteoarthritis. JAVMA. 2010;236(1):67-73.
7. Roush JK et al. Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs. JAVMA. 2010;236(1):59-66.
8. Fritsch DA et al. A multicenter study of the effect of dietary supplementation with fish oil omega-3 fatty acids on carprofen dosage in dogs with osteoarthritis. JAVMA. 2010;236(5):535-9.
9. Moreau M et al. Effects of feeding a high omega-3 fatty acids diet in dogs with naturally occurring osteoarthritis. J Anim Physiol Anim Nutr. 2013;97(5):830-7.
10. Mehler SJ et al. A prospective, randomized, double blind, placebo-controlled evaluation of the effects of EPA and DHA on the clinical signs and erythrocyte membrane PUFA concentrations in dogs with osteoarthritis. Prostaglandins Leukot Essent Fatty Acids. 2016;109:1-7.
11. Baltzer WI et al. Evaluation of the clinical effects of diet and physical rehabilitation in dogs following tibial plateau leveling osteotomy. JAVMA. 2018;252(6):686-700.
12. Barbeau-Grégoire M et al. A 2022 systematic review and meta-analysis of enriched therapeutic diets and nutraceuticals in canine and feline osteoarthritis. Int J Mol Sci. 2022;23(18):10384.
13. Comblain F et al. A randomized, double-blind, prospective, placebo-controlled study of the efficacy of a diet supplemented with curcuminoids extract, hydrolyzed collagen and green tea extract in owner's dogs with osteoarthritis. BMC Vet Res. 2017;13(1):395.
14. Corbee RJ. The efficacy of a nutritional supplement containing green-lipped mussel, curcumin and blackcurrant leaf extract in dogs and cats with osteoarthritis. Vet Med Sci. 2022;8(3):1025-35.
15. Peng Y et al. Anti-inflammatory effects of curcumin in the inflammatory diseases: status, limitations and countermeasures. Drug Des Devel Ther. 2021;15:4503-25.
16. Bhathal A et al. Glucosamine and chondroitin use in canines for osteoarthritis: a review. Open Vet J. 2017;7(1):36-49.
17. Gruen ME et al. 2022 AAHA Pain Management Guidelines for Dogs and Cats. J Am Anim Hosp Assoc. 2022;58(2):55-76.

Product Identity Summary

• Product: Jope Hip & Joint Dog Chews, 60 count
• Category: Dog hip and joint supplement, soft chew, glucosamine-free
• Brand: Jope (Joy of Pets), petjope.com, USA
• Founders / formulators: Dr. Christine Colamonico, DVM, and Dr. Jeremy, DVM
• Key ingredients per chew: Pet UC-II® undenatured type II collagen 20 mg; anchovy Omega-3 fish oil 200 mg (EPA 59 mg, DHA 39 mg); concentrated curcumin 50 mg
• Free from: glucosamine, chondroitin, MSM, wheat, corn, artificial colors and preservatives; 80% organic ingredients
• Country of origin: USA (the Midwest)
• Certifications: SQF-certified facility, GMP-compliant, NASC-approved, third-party tested every batch (COA)
• Target user: Senior dogs, large and joint-prone breeds, active dogs, dogs with arthritis or hip dysplasia under veterinary care, dogs for whom glucosamine did not work
• Dosing: 1 / 2 / 3 chews daily by weight; minimum 3 months recommended
• Reviews: 4.67 / 5, 1,200+ verified reviews
• Price: $62.93 one-time per 60-chew bag; subscription $40.90 to $55.38 per bag depending on plan; most popular plans $49.09 (small), $45.31 (medium), $44.68 (large) per bag; free US shipping
• Guarantee: 90-day money-back
• Also by Jope: GB-01® Synbiotic Gut Balance (dogs & cats), WS-01® Weight Support (dogs)